Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in nuclear DNA. These lesions disrupt energy production and activate ...

Researchers from Karolinska Institutet have discovered how mammalian cells prevent the gradual buildup of harmful mutations in mitochondrial DNA, the small but vital genome that powers every cell. The ...

An ancient fragment of bone discovered in the Crimean cave of Starosele is changing what we think about how and where Neanderthals migrated. The fragment, now known as Star 1, turned out to be ...

The world's oldest DNA comes from a 2.4 million-year-old ecosystem in Greenland. Will scientists eventually sequence even older DNA? When you purchase through links on our site, we may earn an ...

Mitochondria act as energy factories in cells and have their own, separate DNA. Mutations to mitochondrial DNA (mtDNA) have been observed in cancer, but it has been unclear how these changes might ...

New molecule halts mitochondrial DNA loss before it triggers inflammation. When environmental stress harms DNA, it can set off a cascade of failures linked to heart conditions, neurodegeneration and ...

One study reported 8 live births from 22 women with pathogenic mtDNA variants who underwent mitochondrial donation through pronuclear transfer. None had signs of mitochondrial disease and heteroplasmy ...

Eight healthy babies have been born in the U.K. using a new IVF technique that successfully reduced their risk of inheriting genetic diseases from their mothers, the people behind a world-first trial ...