The T2T variant team documented major improvements in identifying and interpreting genetic variants using the new T2T sequence compared to the standard human reference genome. “The new human genome is ...

"T2T genome assemblies grant access to difficult-to-sequence regions, which opens up a myriad of groundbreaking research possibilities, such as creating completely new crop varieties that cater to ...

More information: Weixue Mu et al, The haplotype-resolved T2T genome for Bauhinia × blakeana sheds light on the genetic basis of flower heterosis, GigaScience (2025). DOI: 10.1093/gigascience/giaf044 ...

At the same time as the T2T Consortium was working to assemble the full human genome, genomicists had begun to reckon with the field’s lack of diversity. A large majority of human genomics data has ...

However, This gap-free reference genome, the first T2T reference genome for fruit trees., for the PN40024 provides important resources for grapevine genetics and breeding. Introduction of Zhou’s Lab ...

T2T-Y, in combination with the group's previous reference genome, T2T-CHM13, represents the world's first complete genome for the half of the population with a Y chromosome.

When scientists and clinicians study an individual’s genome, they compare the individuals’ DNA to that of a standard reference to determine where there is variation. Until now, the Y chromosome ...

A team of almost 100 scientists part of the Telomere-to-Telomere (T2T) Consortium has successfully sequenced the most complete human genome yet.

Over the past few years, the Telomere-to-Telomere (T2T) consortium, a collaborative project funded by the National Human Genome Research Institute (NHGRI), part of the NIH, used multiple DNA ...

Sequencing the entire human genome has opened new avenues in genetic research. The T2T Consortium recently finished a complete assembly of a human Y chromosome and non-human ape genomes, and McCoy's ...

The T2T-Y chromosome sequence identified an additional 42 protein-coding genes that had not previously been studied and added an additional 30 million base pairs to the existing reference human ...

"T2T genome assemblies grant access to difficult-to-sequence regions, which opens up a myriad of groundbreaking research possibilities, such as creating completely new crop varieties that cater to ...