Two words can sum up the Week 12 matchup between the visiting San Francisco 49ers and the host Green Bay Packers: utter domination. The Packers cruised to a 38-10 victory, marking the franchise's largest win against the 49ers ever,

Mike Florio and Chris Simms unpack the Bills dominant victory over the 49ers in the snow in Week 13, and why Buffalo is "no question" one of the best teams in football.

It looks like the San Francisco 49ers might get their quarterback back under center in time for a Week 13 matchup with the Buffalo Bills. QB Brock Purdy injured his shoulder in Week 11 against the Seattle Seahawks and wound up missing the team’s blowout Week 12 loss to the Green Bay Packers.

The San Francisco 49ers are extremely banged up going into their Week 13 showdown with the Buffalo Bills. However, they will at least have starting quarterback Brock Purdy this week after he missed Week 12 with a shoulder injury.