Israel and Iran launched a new round of attacks as the conflict between the two heavily armed rivals enters its fifth day.

Israel’s military headquarters were struck after Iran’s Islamic Republic unleashed a barrage of missiles on central Tel Aviv late Friday night, causing “significant damage” to the Jewish state’s equivalent of the Pentagon.

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Aerial attacks between Israel and Iran continued overnight into Monday, marking a fourth day of strikes following Israel's Friday attack. That surprise strike hit the heart of Iran's nuclear program, killing several nuclear scientists as well as high-ranking military leaders, according to Israeli officials.

Israeli citizens were ordered to head to bomb shelters on Friday night amid retaliatory missile strikes from Iran.

The Israeli military said it killed Ali Shadmani, one of Iran's most senior military commanders, in an airstrike in Tehran. He had only been in the job for about four days after Israel killed his predecessor as commander of the central headquarters,

The Israel Defense Forces (IDF) dealt another major blow to Iran as it eliminated overnight the most senior military commander in the regime