Investigators have unveiled for the first time that changes in certain genes affect an aggressive cancer, T-cell acute ...

Pharmacogenomics studies how individuals respond to drugs based on their genetic code. Using that knowledge to guide prescribing in routine care could lead to better outcomes for patients and save ...

In the next sections, we highlight the most promising applications of pharmacogenomics by providing some examples of diseases in which it has been implemented in the clinic for defining risk for ...

The field of pharmacogenomics integrates genomic data with pharmacology to customize drug treatments for individual patients. This presentation aims to educate clinical researchers and healthcare ...

Summary Motivation: Integrating pharmacogenomics (PGx) into clinical practice presents a significant opportunity to improve medication management, especially for patients with chronic diseases like ...

Pharmacogenomics allows doctors to tailor treatments based on the genetic profiles of individual patients, improving outcomes and reducing the risk of side effects. The potential of pharmacogenomics ...

Pharmacogenomics pilot studies at HMC has been ongoing and many patients benefited from them, and it will continue to be one of the successful components for implementing pharmacogenomics clinically.

For example, 70% to 80% of metoprolol’s metabolism is fulfilled by CYP2D6. Higher prevalence of CYP2D6 PM is found in those of European ancestry.

For example, CPIC guidelines note clinically actionable gene/drug pairs to guide providers through translating genetic testing into treatment decision making. 69 Another example is PharmGKB, which ...